Dr. Donna H. Ryan (Click to learn more about Dr. Donna H. Ryan)

The Buildleaf® GLP-1 Nano Microneedle Patch, developed by The Obesity Society, combines advanced SMGT-GLP-1 technology with Matrixyl 3000 to promote weight loss, regulate blood sugar, and improve metabolic balance. It precisely delivers active ingredients to the skin’s deeper layers, aiding insulin regulation, reducing fat, and enhancing health. Simultaneously, Matrixyl 3000 boosts skin regeneration, improving firmness and skin texture during weight loss. Designed by obesity experts after years of research, this innovative patch offers a comprehensive solution for body shaping, skin tightening, and achieving long-term health goals.

 Obesity is a silent killer—slowly destroying your body from within. It crushes organs, clogs arteries, loosens skin, and pushes you toward life-threatening diseases, trapping you in a cycle of medication and painful treatments.

 Buildleaf® helps you say goodbye to the long and painful treatment process and the harmful chemicals!

Unlock the Golden Triangle:SMGT-GLP-1, Collagen Peptides, and Matrixyl3000 work together to support fat reduction, skin tightening, and natural appetite control.

Clinically tested by endocrinologist, Buildleaf® SMGT-GLP-1 Nano Microneedle Patch can significantly improve obesity and other health issues within just 3 week.

Here’s what our customers are really saying – real stories, real results.

“I suffer from both obesity and diabetes, and I had been receiving SMGT-GLP-1 (also known as semaglutide) treatments at the hospital. You might wonder why I suddenly switched to the Buildleaf® SMGT-GLP-1 Nano Microneedle Patch. Honestly, semaglutide is an excellent treatment — shortly after each injection, my appetite decreased, I lost weight quickly, and my blood sugar levels dropped.

But sticking to regular injections isn’t easy. On injection days, I’d always find excuses to skip — the cost, the hunger, scheduling conflicts, or even something as simple as bad weather would stop me. Over time, this inconsistency affected the results.

That’s why the Buildleaf® SMGT-GLP-1 Nano Microneedle Patch is perfect for someone like me who struggles with consistency. I can apply it easily at home, and the slow-release formula works for a full 24 hours, helping me control my appetite steadily. Plus, it’s very affordable — it makes SMGT-GLP-1 accessible for anyone looking to lose weight and manage their blood sugar.

What surprised me even more is that Buildleaf®  Nano Microneedle Patch is different from other fast weight-loss products. My skin didn’t sag after losing weight — instead, it became noticeably firmer and more toned during the process.“

“For all these years, I’ve really been “fighting” with my diet. As a diabetic, there are so many things I can’t eat—just a little slip-up and my blood sugar spikes. What’s even more frustrating is that despite all my efforts, my weight hasn’t changed at all, and my blood sugar is still all over the place. My doctor even told me that some foods might help with weight loss, but they don’t do anything for blood sugar control, which was so disheartening.

I’ve also tried other weight loss products before—yes, I lost a bit of weight, but my skin ended up loose and saggy, and I looked more tired and drained. But the Buildleaf® SMGT-GLP-1 Nano Microneedle Patch is different. It contains Matrixyl 3000, and the firming effect is really noticeable—my skin not only didn’t loosen, it actually feels firmer! I’ve used it consistently for 84 days, and the results are amazing: I’ve lost several kilos, my blood sugar is back to normal, and I look younger. My friends have even commented on how much more vibrant I look! It’s so easy to use—just once a week—and I can eat whatever I want, and it helps automatically control my portion sizes. It’s honestly incredible!

If I hadn’t seen the promotion for this product by chance at the pharmacy, I might have never discovered such an amazing gem.”

“I had never used 𝐒𝐌𝐆𝐓-𝐆𝐋𝐏-𝟏 treatment before, so before purchasing Buildleaf®  , I did a lot of research and read through several case studies. I confirmed that 𝐒𝐌𝐆𝐓-𝐆𝐋𝐏-𝟏 is a great solution for weight loss. Out of all the options, the Buildleaf®  Nano Microneedle Patch turned out to be the best choice. As I expected, during the first two weeks of use, I didn’t experience any discomfort. The results were very consistent and gradual. It helped me slowly control my appetite, and I noticed that my metabolism sped up significantly. My digestion improved, and the feeling of fullness lasted longer. After 9 weeks, I went from 260 lbs to 148 lbs. The results came even faster than what I read online about people getting 𝐒𝐌𝐆𝐓-𝐆𝐋𝐏-𝟏 injections at medical facilities! That’s because Buildleaf®  has higher efficacy and better adherence to the plan. I honestly think everyone should give the 𝐒𝐌𝐆𝐓-𝐆𝐋𝐏-𝟏 Microneedle Patch a try—it’s a great new treatment option.”

I’m 37 years old, and after having my second child, my belly turned into the typical “mommy belly” – loose and wrinkled. I felt terrible and didn’t even want to exercise because my belly would jiggle with every step. I tried cocoa butter and massages for two months, but nothing really changed. My doctor suggested surgery, but I didn’t want any scars or the high costs. So, my husband ordered the  Buildleaf® SMGT-GLP-1 Nano Microneedle Patch with Advanced Peptides and Matrixyl 3000 for me. Not only does it help with weight loss, but it also tightens my skin, and it feels amazing. I use it every day, and by the fifth day, I could feel my skin tightening, and I noticed a significant weight drop. After two weeks, my belly was completely back to normal – no wrinkles, no sagging, just firm like when I was 20. I’m planning to get some for my 60-year-old mom next because I believe it will work wonders for her aging arms too.

Total Body Wellness Starts Here — Naturally.

Enhanced GLP-1 Activation：

The Buildleaf® SMGT-GLP-1 Nano Microneedle Patch boosts GLP-1 activity to support healthy blood sugar, appetite control, and weight management. It delivers SMGT-GLP-1, a GLP-1 receptor agonist that mimics the natural hormone—stimulating insulin, suppressing glucagon, and reducing hunger.

To extend its effects, the patch also includes a DPP-4 inhibitor. DPP-4 is a body enzyme that breaks down GLP-1 and GIP, two key incretins that regulate post-meal insulin response. By blocking DPP-4, the patch helps maintain higher levels of active GLP-1 for longer-lasting metabolic benefits.

This dual-action approach promotes sustained appetite suppression, better glucose control, and effective, lasting slimming.

Firm the skin, repair damage, moisturize and enhance youthful vitality:

For comprehensive skin firming and rejuvenation, our Nano Microneedle Patch meticulously combines advanced ingredients. Matrixyl 3000 and Collagen Peptides synergistically stimulate the skin’s natural collagen production, significantly enhancing elasticity and firmness. Acetyl Hexapeptide-8 targets expression lines by gently relaxing facial muscles, promoting a smoother skin surface. Furthermore, Retinyl Palmitate accelerates cell turnover and boosts collagen synthesis for improved texture, while small molecule Sodium Hyaluronate deeply hydrates and plumps, collectively restoring a more youthful and tightened appearance.

Anti-Aging & Brain Protection:
NAD and MNM, key for energy metabolism and cellular repair, restore energy production and DNA repair, countering the decline in NAD levels with age. Together, Ginkgo biloba, NAD, and MNMsupport brain health, boost memory, and promote a more energized, youthful body by improving circulation, repairing cells, and reducing oxidative stress.

✅ Pharmacy Times #1 Recommended Over-the-Counter (OTC) Products

✅ Manufactured in a GMP certified facility

✅ FDA Compliant Ingredients

✅ Approved by The Obesity Society of America (TOS)

✅ Suitable for all

✅ Results in as little as 1 week

✅ Long-term results and prevention of various diseases

𝐒𝐌𝐆𝐓-𝐆𝐋𝐏-𝟏, with its unique mechanism of action, has already achieved significant results in diabetes treatment and weight management!

Next-generation pain-free injection Nano Μicroneedle Patch.

How does Buildleaf® SMGT-GLP-1 Nano Microneedle Patch work?

 SMGT-GLP-1
A gut-derived hormone that regulates blood sugar, suppresses appetite, and slows gastric emptying—supporting healthy metabolism, reduced cravings, and long-term fat loss.

Matrixyl® 3000
A powerful peptide complex that stimulates collagen and elastin production, visibly reducing fine lines and improving skin firmness and elasticity.

 Collagen Peptides
Rich in essential amino acids, they help strengthen skin structure, boost elasticity, and support hydration from within for a smoother, plumper appearance.

 Acetyl Hexapeptide-8 (a.k.a. “Botox-like peptide”)
Relaxes facial muscle tension, helping reduce the appearance of dynamic wrinkles, especially around the eyes and forehead.

 Sodium Hyaluronate
A deeply hydrating form of hyaluronic acid that penetrates skin layers to attract and retain moisture, leaving skin plump, smooth, and supple.

Check out more of our customers’ satisfaction feedback!

“I used to feel insecure about the swollen lymph nodes on my neck, until I tried Buildleaf®. I was skeptical at first, but within days the swelling reduced. With continued use, the results kept improving. I’ve regained my confidence—and my jawline!”
— Victoria Anastasia, Victoria, Texas

“Carrying extra weight around my stomach had started to feel heavy and uncomfortable—not just physically, but energy-wise too. I gave Buildleaf® SMGT-GLP-1 Nano Microneedle Patch a try, and within days, my midsection felt lighter and more supported. It wasn’t about looks—it just helped my body feel more balanced.”
— Daniel Smith, Seattle, Washington, United States

“I started noticing the skin on my arms getting loose and kind of deflated—it felt off, like my body was slipping out of balance. It honestly made me nervous. I tried Buildleaf® hoping to do something proactive. Within days, the skin felt firmer, more supported—like it was actually holding together better. That change alone made a huge difference in how I felt physically.”—Melissa Kramer, Denver, Colorado, United States

Try it now! 9 Million+ Satisfied Customers Over USA

Product Specifications

Patented and Certified

We support Global Delivery

OUR GUARANTEE